Brain Circulation

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 6  |  Issue : 2  |  Page : 116--122

Ruptured Fisher grade 3 blister aneurysms have a higher incidence of delayed cerebral ischemia than ruptured Fisher grade 3 saccular aneurysms


Tejas Karnati1, Tamar R Binyamin1, Brian C Dahlin2, Ben Waldau1 
1 Department of Neurosurgery, UC Davis Medical Center, Sacramento, CA, USA
2 Department of Radiology, UC Davis Medical Center, Sacramento, CA, USA

Correspondence Address:
Dr. Ben Waldau
Department of Neurosurgery, UC Davis Medical Center, 4680 Y Street, ACC 3740, Sacramento, CA 95811
USA

BACKGROUND: Blister aneurysms are a rare subclass of aneurysms, which remain challenging to treat both with open cerebrovascular and endovascular techniques, and clinicians continue to see poor outcomes in some cases despite improvements in technology. Based on our clinical observations, we hypothesized that patients with a Fisher grade 3 subarachnoid hemorrhage (SAH) from a ruptured anterior circulation blister aneurysm are significantly more likely to develop poor outcome due to delayed cerebral ischemia than patients with a Fisher grade 3 SAH from a ruptured anterior circulation saccular aneurysm. METHODS: In this consecutive case series, we reviewed management, outcomes, and rates of delayed cerebral ischemia for all ruptured anterior circulation blister aneurysms from 2012 to 2018 at our institution and compared them to a concurrent cohort of ruptured saccular anterior circulation aneurysms. A blister aneurysm was defined as an aneurysm that arises from a nonbranching point and demonstrates hemispherical anatomy on diagnostic angiography. RESULTS: We identified 14 consecutive ruptured anterior circulation blister aneurysms. Thirteen aneurysms were treated operatively– 5 with clip remodeling and 8 with flow diversion embolization. While clip remodeling had a high intraoperative rupture rate (80%), there was only one (12.5%) intraoperative rupture with flow diversion embolization. Outcomes were worsened by delayed cerebral ischemia from vasospasm in patients with Fisher 3 hemorrhages from blister aneurysms (86%). The rate of delayed cerebral ischemia from vasospasm was significantly higher for ruptured blister aneurysms than for a concurrent cohort of ruptured saccular aneurysms (8.6%,P = 0.0001). CONCLUSION: Ruptured Fisher grade 3 anterior circulation blister aneurysms have a significantly higher incidence of delayed cerebral ischemia from vasospasm compared to saccular aneurysms, regardless of the treatment modality.


How to cite this article:
Karnati T, Binyamin TR, Dahlin BC, Waldau B. Ruptured Fisher grade 3 blister aneurysms have a higher incidence of delayed cerebral ischemia than ruptured Fisher grade 3 saccular aneurysms.Brain Circ 2020;6:116-122


How to cite this URL:
Karnati T, Binyamin TR, Dahlin BC, Waldau B. Ruptured Fisher grade 3 blister aneurysms have a higher incidence of delayed cerebral ischemia than ruptured Fisher grade 3 saccular aneurysms. Brain Circ [serial online] 2020 [cited 2023 Feb 1 ];6:116-122
Available from: http://www.braincirculation.org/article.asp?issn=2394-8108;year=2020;volume=6;issue=2;spage=116;epage=122;aulast=Karnati;type=0